Today, thousands of people suffering with MS are turning to cannabinoids in search of relief from the debilitating symptoms of the disease. CBD, the nonpsychotropic cannabinoid derived from medicinal hemp, activates the CB2 receptors within the body’s natural endocannabinoid system. This system controls homeostasis which is the body’s ability to create stability within the body and promote the healing process.
CB1 and CB2 receptors are found in all body organs and systems. If there is an absence or deficiency in the production of endocannabinoids, the receptors will not be able to function properly.
CB2 agonists do not produce psychoactive effects. CBD triggers CB2 receptors which are located on immune cells and related organs, as well as the gastrointestinal system. Because CB2 receptors modulate the immune response, CBD can exert its anti-inflammatory effects throughout the body. Numerous studies have shown CBD to have an antioxidant and neuroprotectant effect as well. In fact, the Department of Health and Human Services holds a patent number US6630507B1 called Cannabinoids as Antioxidants and Neuroprotectants.
In contrast, THC, the major cannabinoid in marijuana, activates the CB1 receptors predominantly located in the brain, and central nervous system. Although marijuana has been shown to be therapeutic for people suffering from multiple sclerosis, THC is associated with the psychoactive “high” from cannabis, and may increase anxiety in some individuals. THC has also been shown to affect gait, which increases falls risk.
In Multiple Sclerosis, damage to the myelin sheath disrupts nerve signals between the brain, spinal cord, and the body. Spasticity is the most debilitating symptom of MS and effects the patient’s quality of life. The research suggests that CBD oil helps reduce muscle spasticity, which not only alleviates some of the pain associated with MS, but also allows those with MS to perform activities of daily living more efficiently and for longer.
Unlike the current standard medications prescribed which can have serious long term effects on the body, CBD has an excellent safety profile, and will not affect gait, or mental functioning. Giving Earth Nutraceuticals Hemp CBD contains a high content of CBD and is certified ZERO THC, making GEN CBD and excellent choice for those individuals who don’t want the high feeling or stigma surrounding the use of medical marijuana.
The National Multiple Sclerosis Society has taken a supportive stance on cannabinoids, stating, “The Society supports the rights of people with MS to work with their MS health care providers to access marijuana for medical purposes in accordance with legal regulations in those states where such use has been approved. In addition, the Society supports advancing research to better understand the benefits and potential risks of marijuana and its derivatives as a treatment for MS.”
Studies have shown CBD to be anti-inflammatory, antioxidant, and neuroprotective, and these studies also suggest that cannabinoids could be a potential treatment for neurological disorders, because of its ability to reduce neurotoxicity and protect the brain. Because neuroinflammation plays a large role in the neurodegenerative processes, and cannabinoids modulate the immune response during the inflammatory process, stimulation of CB2 receptors have opened the door for the development of new neuroprotective therapies.
What does this mean for MS patients? Further studies will be needed to confirm whether multiple sclerosis is in fact a deficiency of the body’s natural endocannabinoid system, and expand the body of knowledge on the mechanism of action of CBD in the MS disease process, but many patients are currently finding relief from some symptoms utilizing CBD.
Talk to your doctor about how Giving Earth Nutraceuticals CBD can safely be incorporated into your plan of care.